TCGA-based bioinformatics analysis was carried out; as a result, SUV39H2, together with additional new genes (DNMT3B, SUV39H1, AURKB, and EZH2) was remarkably upregulated within TN disorders, which was positively related to Ki67 upregulation, tumor grade, and TN status. This evidence concerns the gene EZH2 and neoplasm.