ADCY1 and schizophrenia: Although how ADCY1 regulates the hallmark schizophrenia symptoms remains unclear, ADCY1 deficiency leads to impaired LTP (Villacres et al., 1998; Zheng et al., 2016) and spatial memory (Wu et al., 1995) and maldevelopment of the sensory cortex (Suzuki et al., 2015).