For 1G EGFR-TKIs with chemotherapy, neutropenia, anemia, and thrombocytopenia were more common, the rates of grade 3 for these hematological toxicities were 33.3% (n = 2), 25.0% (n = 3), and 16.7% (n = 2). Here, EGFR is linked to Decreased total neutrophil count.