It has been studied in the literature that STAT3 is activated in EGFR mutant NSCLC (Chaib et al., 2017), Western blot analysis showed that the phosphorylation level of STAT3 decreased (Figures 3A,B), Orozco-Morales M (Orozco-Morales et al., 2021) found that S-allylcysteine (SAC) can reduce NF-κB expression in H1975 cells, thereby inhibiting tumor cell proliferation and inducing apoptosis. The gene discussed is EGFR; the disease is non-small cell lung carcinoma.