FBXW7 and acute kidney injury: This study concluded that CaMKIV preserved mTOR expression by inhibiting glycogen synthase kinase-3 beta (GSK3β) and F-box and WD repeat-containing protein 7 (FBXW7) mediated ubiquitination and proteasomal degradation, and promoted autophagy in LPS-induced AKI (Zhang et al., 2014).