TNF and metabolic dysfunction-associated steatotic liver disease: Wang et al. found that the levels of IL-1β, IL-6, and TNF-α in the liver tissue of rats in the NAFLD model group were significantly increased, and total flavonoids of Scutellaria baicalensis could reduce these inflammatory factors, suggesting that total flavonoids in Scutellaria baicalensis could reduce the inflammatory response in the liver of rats in the NAFLD model group (Mengmeng et al., 2022).