For example, Wang et al. found five hub genes (JUN, SLC2A1, TFRC, ALB, and NFE2L2) that are closely associated with ferroptosis in AD and can differentiate AD patients from controls; these genes can be used as potential ferroptosis-related biomarkers for disease diagnosis and therapeutic monitoring (Wang et al., 2022). The gene discussed is TFRC; the disease is Alzheimer disease.