When treating complete Freund’s adjuvant-induced arthritis, AG inhibits a series of molecules related to arthritis, such as cyclooxygenase-2 (COX-2), NF-κB, p-p38, CD40, TNF-α, IL-1β, and IL-6 (Gupta et al., 2020). This evidence concerns the gene NFKB1 and Arthritis.