KDM1A and breast cancer: Capsaicin (Figure 6, 23), a bioactive compound from chili peppers with the broad spectrum of anticancer activity in various subtype of BC cells (Chou et al., 2009; Thoennissen et al., 2010; Wu et al., 2020; Chen et al., 2021), was found to act as reversible LSD1 inhibitor with an IC50 value of 0.6 μM (Jia et al., 2020).