Notably, MRC2 expression in BLCA, COAD, READ, PAAD, and UMV was positively correlated with LAG3, NRP1, CTLA4, PDCD1 (PD-1), CD274 (PD-L1), and PDCD1LG2(PD-L2). This evidence concerns the gene CD274 and pancreatic adenocarcinoma.