Proteins associated with ALS (FUS, TDP-43, hnRNPA1, etc.), Alzheimer’s (Tau), and Parkinson’s (α-synuclein) undergo both LLPS and aggregation into fibers (Gotz et al., 2001; Roberson et al., 2007; Sreedharan et al., 2008; Vance et al., 2009; Kim et al., 2013; Wegmann et al., 2018; Ray et al., 2020). Here, TARDBP is linked to amyotrophic lateral sclerosis.