BARD1 and Ewing sarcoma: We have previously reported a patient with Ewing sarcoma who harbors a heterozygous pathogenic germline BARD1 variant (c.176_177AG; p.E59Afs*8) that results in a frameshift that introduces a premature stop codon within the RING domain of BARD1 (ref. 11; Table 1, footnote “a”, index case).