HIF1A and cancer: According to the KEGG enrichment, a total of 1,088 alternatively spliced DEmRNAs were enriched in 279 pathways between normoxic (21% O2, TN and LN) and hypoxic (2% O2, TL and LL) groups, of which 35, 17, and 25 genes were enriched in MAPK signaling pathway, HIF-1 signaling pathway, and proteoglycans in cancer.