For instance, MAPK3 (ERK1), a component of the Ras-MAPK pathway, has been identified as the probable causal gene underlying the association signal at its locus in the largest schizophrenia genome-wide association study conducted to date (Schizophrenia Working Group of the Psychiatric Genomics Consortium et al., 2020). The gene discussed is MAPK3; the disease is schizophrenia.