In multivariate logistic regression analysis, independent predictors of surgical remission were normoprolactinemia at diagnosis (OR=3.86, p=0.096), DG tumor in EM (OR=3.05, p=0.181), lower fasting GH concentration at diagnosis (OR=0.92, p=0.026) and smaller maximal tumor diameter (OR=0.87, p=0.069). The gene discussed is GH1; the disease is neoplasm.