(24) reported that the previously well-known mutations for adrenocortical adenoma (GNAS, CTNNB1, PRKAR1A, PRKACA, PDE11A, PDE8B, KCNJ5, CACNA1D) (31) and PCC (RET, VHL, NF1, SDHA, SDHB, SDHC, SDHD, SDHAF2, TMEM127, MAX, EGLN1(PHD2), EPAS1(HIF2A), KIF1B, MET, FH, and H-RAS) (32) were not detected in their MCMT. This evidence concerns the gene GNAS and adrenal cortex adenoma.