Other gene polymorphisms, e.g., PCSK9 gene E670G polymorphism (37), ALDH2 gene G487A polymorphism (38), CDKN2B-AS1 gene rs4977574 A/G polymorphism (39), and FVII gene R353Q polymorphism (40), may also be involved with CAD susceptibility. This evidence concerns the gene PCSK9 and coronary artery disorder.