On the basis of the nodal metastasis status, the CCDC6 expression was higher in patients with HCC classified as N0 (No regional lymph node metastasis) and in those with CCA classified as N0 or N1 (metastases in 1 to 3 axillary lymph nodes; Figure 2C). This evidence concerns the gene CCDC6 and hepatocellular carcinoma.