The result suggested genes which participate in cell adhesion and invasion including CORO1C, VCL, CAV1, ATP2B4, ERC, PPP1R12A, PALLD, FLNA, AHNAK was confirmed down-regulated in tumor lesion compared with tissues adjacent to carcinoma, which was the same as our prediction in Figure 5E. This evidence concerns the gene ATP2B4 and carcinoma.