CLK2 and urinary bladder carcinoma: Then, 9 target genes that were differentially expressed between bladder cancer and normal samples were screened (FDR < 0.05, Supplementary Figure 3), in which upregulated expression of RHBG, PAQR6, CLK2, KRTCAP2, FLAD1, HCN3 were correlated with bad survival of patients with bladder cancer (Supplementary Figure 4).