Gaudino et al. stressed out that 174G-C polymorphism IL6 correlated with the onset of AKI after the use of CPB (Gaudino), while Stafford-Smith et al. found two allels IL6-572C and angiotensinogen 842C are connected with post-CPB AKI, also polymorphism for APO-E. This evidence concerns the gene IL6 and acute kidney injury.