The BTG3-correlated genes were involved in RNA transport, splicing and degradation, DNA replication and cell cycle, proteasomal degradation for gastric cancer, cell cycle, DNA replication, and mismatch repair, TNF and NF-κB signal pathways for lung cancer, ribosome and spliceosome, and metabolism of amino acids for breast cancer, neural diseases, viral infection, oxidative phosphorylation for ovarian cancer. The gene discussed is TNF; the disease is breast cancer.