RORC and cancer: RORC was differentially expressed in 12 cancers compared to adjacent normal tissues (BRCA, CHOL, COAD, ESCA, HNSC, KIRP, LUAD, LUSC, PRAD, READ, STAD, and THCA), with RORC expression being significantly higher in BRCA, LUAD, and PRAD than in adjacent normal tissues (Figure 2A).