TGFB1 and cancer: Consistent with our study, a previous study performed an integration analysis of TGF-β superfamily genetic alterations in 9,125 tumor samples from 33 cancer types, elucidated the salient characteristics of TGF-β-related genes in a large group of different cancer types, and found high-frequency genetic alterations in the TGF-β superfamily across cancer types (Korkut et al., 2018).