Similarly, circ-CUX1 binds to EWS RNA-binding protein 1 (EWSR1) to promote its interaction with MYC-associated zinc finger protein (MAZ), transactivating MAZ, and modulating CUX1 expression to facilitate the metabolic reprogramming and progression of neuroblastoma (NB) [59]. This evidence concerns the gene ZNF146 and neuroblastoma.