According to the data from 306 CESC samples and corresponding 13 normal samples, the average mRNA expression level of the 6 hub genes was as follows: ASPM (Tumor: Normal = 3.74 ± 0.713 : 0.365 ± 0.663, P < 0.001); CDC20 (Tumor: Normal = 6.61 ± 0.637 : 1.17 ± 1.238, P < 0.001); DLGAP5 (Tumor: Normal = 4.038 ± 0.74 : 0.371 ± 0.724, P < 0.001); BUB1B (Tumor: Normal = 3.896 ± 0.753 : 0.609 ± 0.895, P < 0.001); CDCA8 (Tumor: Normal = 4.579 ± 0.688 : 0.947 ± 0.717, P < 0.001); NCAPG (Tumor: Normal = 3.828 ± 0.615 : 0.495 ± 0.817, P < 0.001). The gene discussed is CDCA8; the disease is neoplasm.