In contrast with coronary artery disease (CAD), coronary artery aneurysms (CAA) with KNG1 with histidine proline glycoprotein and SERPINC1 have anti-inflammatory and anticoagulant properties, and their low levels cause inflammation and endothelial damage resulting in coronary artery dilatation and aneurysm formation. Here, KNG1 is linked to coronary artery disorder.