IAP family members include survivin, inhibitors of apoptosis (c-IAP1 and c-IAP2), X-linked inhibitor of apoptosis (XIAP), BIR-repeat-containing ubiquitin-conjugating enzyme (BRUCE/Apollon), IAP-like protein 2 (ILP-2), neuronal apoptosis inhibitor protein (NAIP) and melanoma IAP (ML-IAP/Livin). The gene discussed is XIAP; the disease is melanoma.