Furthermore, anthocyanins can directly transmit antioxidant effects through their antioxidant properties, and indirectly combat oxidative stress and inflammatory signals in cells within atherosclerosis (AS) plaques by inducing nuclear factor erythroid 2-related factor 2 (Nrf2) activation and antioxidant gene expression, thus effectively preventing AS (6). This evidence concerns the gene NFE2L2 and atherosclerosis.