TF and metabolic dysfunction-associated steatotic liver disease: Consistently, we found that genetic liability to higher systemic iron status was significantly and positively associated with NAFLD risk, odds ratios estimation of per SD increase in biomarker levels were 1.19 (95% CI 1.07–1.31, P = 5.3 × 10−3) for serum iron, 1.15 (95% CI 1.06–1.24, P = 2.3 × 10−3) for transferrin saturation, 1.57 (95% CI 1.29–1.85, P = 1.7 × 10−3) for ferritin, and 0.8 (95% CI 0.66–0.94, P = 1.9 × 10−3) for serum transferrin (Figure 5).