Here, detected the phosphorylation levels of STAT1 and STAT3 in four different lung adenocarcinoma cells and found that the phosphorylation level of STAT1 in H1299 (EGFR-WT) cells was higher than that of PC-9 (EGFR-19del), H1975 (EGFR-T790M and L858R combined mutation), and H3255 (EGFR-L858R mutation) cells (Figure 1(a)), while the phosphorylation level of STAT3 was lower than that of the other three cells (Figure 1(b)). Here, EGFR is linked to lung adenocarcinoma.