Small molecule MSA-2 is a potential non-cyclic dinucleotide STING agonist in pre-clinical stage, which significantly inhibits tumor growth and achieves long-term survival rates of 35% and 100% in MC38 mice model with dosage administered orally (80 mg/kg) or subcutaneously (50 mg/kg) 3. The gene discussed is STING1; the disease is neoplasm.