We also noticed that the expressions of CD68 (which can bind and internalize ox-LDL and apoptotic cells 57, 58) and CD32 (FcγRIIA, significantly decreased on peripheral monocytes in AS patients 59) were both significantly (p.adj < 0.05) downregulated on ncMon in the diseased groups rather than NC group, accompanied by upregulated CD11b expression in CAS (p.adj < 0.05) and ASCVD (p.adj = 0.062) groups (Figure S2F). The gene discussed is CD68; the disease is atherosclerosis.