MCM6 and metastatic malignant neoplasm in the lymph nodes: Univariate and multivariate Cox regression analyses comprising MCM6 and other risk factors such as age, Lauren subtype, tumor grade, TNM stage, and lymph node metastasis demonstrated that MCM6 was an independent prognostic factor for GC patients (HR, 1.545; 95% confidence interval, 1.093-2.184; P = 0.014; Figure 2I and Table S6).