Such a hypothetical individual presenting mild enamel and/or dentin defects and normal periodontal function could potentially be diagnosed from the dental presentation with amelogenesis imperfecta (AI; OMIM# 301200, 204650, 104500, 612529, 204700, and many more), dentinogenesis imperfecta (DI) type II or III (OMIM# 125490, 125500), dentin dysplasia type II (DD; OMIM# 125420), while potential skeletal effects of a PHOSPHO1 mutation (e.g., scoliosis, fractures, and osteomalacia) may suggest one of the many forms of osteogenesis imperfecta (OMIM# 166200, 166210, and several others). Here, PHOSPHO1 is linked to osteomalacia.