DOCK3 and hypertensive disorder: In addition, there were also statistical differences in age (p < 0.001), education (p < 0.001), gender (p < 0.001), smoker (p = 0.009), tea drinker (p < 0.001), hobby (p < 0.001), hypertension (p = 0.006), physical exercise (p < 0.001), MMSE (P < 0.001), and MoCA (p < 0.001) among the three groups, so these variables would eventually be considered as covariables.