According to the report, during cancer immunotherapy, ferroptosis can be activated by interferon gamma (IFNγ) released from CD8+ T cells, and IFNγ down-regulates the expression of SLC3A2 and SLC7A11 to reduce the uptake of cystine in tumor cells, leading to ferroptosis in tumor cells (Wang, Green et al., 2019). Here, SLC7A11 is linked to neoplasm.