EGFR and esophageal cancer: In patients with head and neck, ovarian, cervical, bladder and esophageal cancers, elevated EGFR levels were found to be a strong prognostic factor and were associated with reduced recurrence-free or overall survival (15), while in patients with gastric, breast, endometrial and colorectal cancers, increased EGFR levels correlated with poor survival rates, but were considered a modest prognostic factor (15).