Taken together, various studies investigating on the effects of Calebin A on different types of tumors and thus its impact on major inflammatory signaling pathways like NF-κB, show that Calebin A as a new compound of turmeric reveals not only anti-oxidative and anti-inflammatory but especially also anti-tumor effects, holding great potential as a phytopharmaceutical agent in the treatment of diseases. The gene discussed is NFKB1; the disease is neoplasm.