BRD2 and acute lymphoblastic leukemia: We categorized all unique clonotypes (unique TRB/TRA-CDR3 pair sequences) based on their tissue association into seven possible tissue distribution patterns (tissue specific: tumor, NAT, PBMC; shared by two tissues: tumor-NAT (TN), tumor-PBMC (TP), PBMC-NAT (PN); or shared by all tissues: ALL).