CX3CR1 and neoplasm: T-cell clonotypes restricted to tumor expressed a characteristic set of chemokines and chemokine receptors including CCR1, CCR5 and CXCL5. In contrast, the T-cell clonotypes shared by all tissues expressed a unique group of chemokine ligands and receptors including the pro-inflammatory chemokine receptor CX3CR1 (Figure 5I).