In addition, omentum may play a positive role in promoting the invasion of GC cells through secreted proteins such as interleukin (IL)-6, IL-8, intercellular adhesion molecule 1 (ICAM-1), C-C motif chemokine ligand 2 (CCL2), and oncostatin M (OSM) (68). The gene discussed is CCL2; the disease is gastric cancer.