DDX41 and acute myeloid leukemia: Since the prevalence of patients with germline DDX41 mutations is relatively high among patients with HMMs, retrospective comparison of patients with and without germline DDX41 mutations using large-scale data of some clinical trials was recently reported by Duployez et al.; 191 patients with AML having DDX41 germline mutations and 1,604 DDX41 wild-type patients with AML were compared (16).