Through LASSO analysis, twelve DEGs (ERBB4, FGFR1, SLC28A1, BDH1, PPARGC1A, ABCC8, SLCO1B3, PDSS1, AIFM1, TSFM, HGF, TH) related to lactate metabolism were used to construct a risk score model and used as a prognostic signature for ovarian cancer. This evidence concerns the gene AIFM1 and ovarian cancer.