KEGG pathway analysis indicated that the CCT3 targeted genes were involved in the JAK-STAT3 signaling pathway, the Hippo signaling pathway, the WNT signaling pathway, and two pathways centralizing in leukemia-related terms (namely acute myeloid leukemia and chronic myeloid leukemia) (41, 51, 52). The gene discussed is CCT3; the disease is leukemia.