MET and neoplasm: Based on our previous work,16 cMBP peptide was selected as the targeting ligand because of its high docking affinity to c-Met and known application in tumor therapy25 and imaging.26,27 This homing peptide may offer many properties including high tumor penetration, low immunogenicity, and cheap synthesis.28 Indocyanine green was chosen as the imaging agent due to its biomedical safeness and high signal-to-background ratio.29