ASF1A and chronic myelogenous leukemia, BCR-ABL1 positive: Similarly, we measured the mRNA and protein expression of ASF1A in bone marrow samples from patients with newly diagnosed CML-CP (n = 43) and CML-BC (n = 24), and both ASF1A mRNA and protein expressions were enhanced in patients with CML-BC than in those with CML-CP (Fig. 1b, c).