In mouse lungs, the conditioned medium from cancer cells resulted in E-selectin-upregulated foci in endothelial cells, correlating well with sites of CTCs attached in the lungs after 5-h injection of CTCs.156 However, if E-selectin is related in the early CTC adhesion or if it conductive to a later enhancing of the reaction of CTCs with endothelial cells would need further investigation. Here, SELE is linked to cancer.