Symptomatic COVID-19 patients had significantly (p < 0.05) higher levels of IL-10, IL-2, IL-2R, IL-6, IL-8 GM-CSF IP-10, TNF-α, IL-4, IL-5, IL-12, IFN-γ and MIP-1β compared to the asymptomatic cases (Fig. 3B). This evidence concerns the gene TNF and COVID-19.