Logistic regression analysis of age, BMI, FPG, HbA1c, FINS, HOMA-IR, TG, TC, LDL-C, HDL-C, LH, FSH, T, SHBG, PRL, and E2 was conducted to analyze the independent correlation between miR-222-3p and diabetic complications in PCOS patients. This evidence concerns the gene SHBG and polycystic ovary syndrome.