In a large study of 5700 COVID-19 patients, the CRP threshold for cytokine storm was determined to be 30 mg/L.24 Increased CRP levels are one of the most highly correlated markers with severe COVID-1935 and were found to decrease in 13/15 COVID-19 cases treated with MSC (Fig. 2A), and in several multi-patient trials.13,17,30,31 Improved oxygenation was accompanied by decreases in CRP and, in the majority of cases, it was reduced below the 30 mg/L thresholds to near normal levels. The gene discussed is CRP; the disease is COVID-19.