TLS/FUS-ERG is mainly reported in AML, but not in myelodysplastic syndrome (MDS) evolved to AML, acute lymphoblastic leukemia (ALL), blast crisis of chronic myelogenous leukemia (CML), and Ewing’s tumors [7–10]. The gene discussed is ERG; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.